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Adenine hydrochloride hydrate

CAS No. 6055-72-7

Adenine hydrochloride hydrate( 6-Aminopurine hydrochloride hydrate )

Catalog No. M19885 CAS No. 6055-72-7

Adenine is a high affinity adenine receptor agonist (Ki = 18 nM at rat adenine receptor). It inhibits forskolin-stimulated cAMP formation in CHO cells transfected with the adenine receptor and also stimulates GTPγS binding (pEC50 values are 8.54 and 7.21 respectively).

Purity : >98% (HPLC)

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Biological Information

  • Product Name
    Adenine hydrochloride hydrate
  • Note
    Research use only, not for human use.
  • Brief Description
    Adenine is a high affinity adenine receptor agonist (Ki = 18 nM at rat adenine receptor). It inhibits forskolin-stimulated cAMP formation in CHO cells transfected with the adenine receptor and also stimulates GTPγS binding (pEC50 values are 8.54 and 7.21 respectively).
  • Description
    Adenine is a high affinity adenine receptor agonist (Ki = 18 nM at rat adenine receptor). It inhibits forskolin-stimulated cAMP formation in CHO cells transfected with the adenine receptor and also stimulates GTPγS binding (pEC50 values are 8.54 and 7.21 respectively).
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    6-Aminopurine hydrochloride hydrate
  • Pathway
    Endocrinology/Hormones
  • Target
    AChR
  • Recptor
    Adenosine receptor
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    6055-72-7
  • Formula Weight
    189.6
  • Molecular Formula
    C5H8ClN5O
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:10 mM
  • SMILES
    O.Cl.Nc1ncnc2[nH]cnc12
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Gorzalka S et al. Evidence for the functional expression and pharmacological characterization of adenine receptors in native cells and tissues. Mol Pharmacol. 2005 Mar;67(3):955-64.
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